产品货号：
Z11245
中文名称：
Arrestin-C/ARR3抗体
英文名称：
Anti-Arrestin-C/ARR3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Arrestin-C/ARR3 Antibody |
| 指标别名 | ARR3,Arrestin C,ARRX,C arrestin,CAR,cArr,Cone arrestin,Retinal cone arrestin 3,X arrestin |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | ARR3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ARR3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ARR3.The immunogen is located within the last 50 amino acids of ARR3. |
| 计算分子量 | 43kDa |
| 成分 | ARR3 antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ARR3 antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Arrestin 3 (ARR3) belongs to the Arrestin family of proteins that function as negative regulators of G protein-coupled receptor (GPCR) signaling (1,2).ARR3 binds the c-Jun N-terminal kinase 3 (JNK3) and scaffolds the apoptosis signal-regulating kinase 1 (ASK1)-MAPK kinase4-JNK3 cascade in a receptor-independent fashion,promoting JNK3 phosphorylation (3,4).ARR3 also mediates the internalization of the C-C chemokine receptor CCR7 upon the binding of its ligand CCL19,but not CCL21,suggesting that it helps mediate CCR7 receptor desensitization (5). |
| Uniprot ID | P36575 |
| 基因名全称 | Arrestin 3,retinal (X-arrestin) |
| 蛋白名全称 | Arrestin 3,retinal (X-arrestin) |
| 推荐稀释比 | ARR3 antibody can be used for detection of ARR3 by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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